{"id":16478,"date":"2020-06-30T08:26:31","date_gmt":"2020-06-30T06:26:31","guid":{"rendered":"https:\/\/asscat-hepatitis.org\/?p=16478"},"modified":"2020-06-30T08:26:31","modified_gmt":"2020-06-30T06:26:31","slug":"un-estudi-amb-un-medicament-mostra-beneficis-a-persones-amb-malaltia-del-fetge-gras","status":"publish","type":"post","link":"https:\/\/asscat-hepatitis.org\/ca\/un-estudi-amb-un-medicament-mostra-beneficis-a-persones-amb-malaltia-del-fetge-gras\/","title":{"rendered":"Un estudi amb un medicament mostra beneficis a persones amb malaltia del fetge gras"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;3.0.106&#8243; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;0px||0px|&#8221; next_background_color=&#8221;#000000&#8243;][et_pb_row custom_padding=&#8221;0px||0px|&#8221; _builder_version=&#8221;3.0.106&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_post_title author=&#8221;off&#8221; date_format=&#8221;d\/m\/Y&#8221; comments=&#8221;off&#8221; featured_placement=&#8221;background&#8221; text_background=&#8221;on&#8221; text_bg_color=&#8221;#ffffff&#8221; module_class=&#8221;ac-post-title-section-0&#8243; _builder_version=&#8221;3.0.106&#8243; title_font=&#8221;Montserrat|600|||||||&#8221; title_text_color=&#8221;#2d2d2d&#8221; title_letter_spacing=&#8221;-1px&#8221; title_line_height=&#8221;1.2em&#8221; meta_font=&#8221;Open Sans||||||||&#8221; meta_text_color=&#8221;rgba(45,45,45,0.5)&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;|20px|20px|20px&#8221; title_text_align=&#8221;center&#8221; meta_font_size=&#8221;13px&#8221; meta_text_align=&#8221;center&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_post_title][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; _builder_version=&#8221;3.0.106&#8243; custom_padding=&#8221;||0px|&#8221; prev_background_color=&#8221;#000000&#8243; module_class=&#8221;ac-post-section-share-rrss&#8221; next_background_color=&#8221;#000000&#8243;][et_pb_row custom_padding=&#8221;||0px|&#8221; custom_margin=&#8221;|||&#8221; _builder_version=&#8221;3.0.105&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_divider color=&#8221;#e20611&#8243; show_divider=&#8221;on&#8221; divider_style=&#8221;ridge&#8221; _builder_version=&#8221;3.0.106&#8243; \/][et_pb_text _builder_version=&#8221;3.0.106&#8243; text_font=&#8221;Montserrat||||||||&#8221; text_text_color=&#8221;#e20611&#8243; text_orientation=&#8221;center&#8221; custom_margin=&#8221;||0px|&#8221; custom_padding=&#8221;|||&#8221; background_layout=&#8221;light&#8221; disabled=&#8221;on&#8221;]<\/p>\n<h5>Desde aqu\u00ed puedes compartir esta publicaci\u00f3n. \u00a1Gracias!<\/h5>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;3.0.106&#8243; custom_padding=&#8221;0px|||&#8221; prev_background_color=&#8221;#000000&#8243;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner admin_label=&#8221;Fila&#8221; _builder_version=&#8221;3.0.106&#8243;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_text admin_label=&#8221;Contenido Entrada 1&#8243; ul_type=&#8221;square&#8221; module_class=&#8221;ac-posts-content&#8221; _builder_version=&#8221;3.0.106&#8243; text_orientation=&#8221;justified&#8221; background_layout=&#8221;light&#8221;]<\/p>\n<h3>Un estudi dut a terme per investigadors de la Universitat de Calif\u00f2rnia a San Diego (Estats Units) ha posat de manifest que un medicament ha mostrat beneficis en persones amb malaltia del fetge gras.<\/h3>\n<p>Publicat a la revista <em>The Lancet Gastroenterology and Hepatology<\/em>, al treball es va injectar als participants un inhibidor antisentit anomenant IONIS-DGAT2 o un placebo. L\u2019inhibidor, produ\u00eft per Ionis Pharmaceuticals, interfereix amb Diacylglycerol-O-acyltransferace o DGAT2, una de les dues formes enzim\u00e0tiques necess\u00e0ries per catalitzar o accelerar la producci\u00f3 de triglic\u00e8rids, un tipus de greix que es troba a la sang. Els alts nivells de triglic\u00e8rids augmenten l\u2019emmagatzematge de greix a tot el cos, incl\u00f2s el fetge.<\/p>\n<p>Els investigadors van trobar que despr\u00e9s de 13 setmanes de tractament, els participants que van rebre l\u2019inhibidor enzim\u00e0tic van experimentar reduccions quantificables en els nivells de fetge gras en comparaci\u00f3 amb el valor inicial, sense nivells elevats de greixos, enzims o sucres a la sang.<\/p>\n<p>No obstant, es van informar sis events adversos greus, incl\u00f2s una aturada card\u00edaca i trombosi venosa profunda, per\u00f2 els investigadors van determinar que els events no estaven relacionats amb el medicament de l\u2019estudi.<\/p>\n<p><em>\u201cTot aix\u00f2 \u00e9s molt encoratjador i defensa el seg\u00fcent pas: assajos a m\u00e9s llarg termini per investigar m\u00e9s a fons el potencial d\u2019aquest medicament en la millora de les caracter\u00edstiques histol\u00f2giques hep\u00e0tiques associades amb la malaltia del fetge gras\u201d<\/em>, han concl\u00f2s.<\/p>\n<p>&nbsp;<\/p>\n<p>Font: <a href=\"https:\/\/m.infosalus.com\/farmacia\/noticia-estudio-medicamento-muestra-beneficios-personas-enfermedad-higado-graso-20200617190033.html\">infosalus.com<\/a><\/p>\n<p>Not\u00edcia tradu\u00efda per l\u2019ASSCAT<\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner admin_label=&#8221;Fila&#8221; 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